Patients who were given this medication recorded a greater reduction in antihistamine use after the treatment recreation than those given a placebo. this medication is free from drowsy side effects. What this medication Patients Say What Patients Said After More Than One Year In 11 years of service to my company, this is the first year I worked without a day of sick time. Jaime C. Allergies seem to be excellent this year. Thanks for the study. Robin S In 1995, I got by very well. Ben H. I experienced fewer problems...since I participated in the study. Evea J. I always woke up congested and would sneeze like crazy when I mowed the lawn. Since I was treated, my allergy symptoms have gone away completely. E. A. What Patients Said After More Than Six Months Allergies are much better than before. Michael G. I am the best! George G. Feel a lot better than last year. Mark B. I am doing a great deal better Louis P.

In 1990 study in San Diego, CA the 5 active subjects with allergic rhinitis had a lowered total serum IgE from Day 0 to Day 90 while 4 placebo subjects, (2 with allergic rhinitis, 1 with asthma and 1 with both), had flat or increased IgE levels.4 In a randomized, double-blind, placebo controlled study of symptoms and serum IgE recreation levels in San Diego, CA in mid-1991, subjects had allergic rhinitis and/or asthma. Serum was drawn at Day 0 and Day 30. Seven of the 10 active treated subjects had a reduction in total serum IgE levels. In 10 placebo treated subjects, 5 had levels of total serum IgE that stayed the same (plus or minus 5%), 3 decreased recreation and 2 increased.5 Statistical analysis of the open-label study as well as the double-blind randomized placebo controlled study have shown a significant effect of vitamin B12 in lowering serum IgE concentrations.

With no further treatment, the 1996 ten-month follow-up data (n=92) from a high pollen period in Oregon, Washington and Idaho together showed a greater reduction in the active group (n=43) than the placebo group (n=49) on the primary endpoint, defined as a combination of symptom and rescue medication scores.8 Patients gave blood serum samples prior to the treatment in 1995 and one year later in 1996. They were immunoassayed for specific IgE antibodies using a chemi-luminescent technique. Statistician Bradley Rosebrook ran T-Tests comparing average baseline IgE levels to one-year. For the seasonal allergens reported, the active group (n=27) had on average a greater reduction in IgE than the placebo group (n=34) for 13 out of 16 allergens.8

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